I really enjoy the Flagship rules (they are what we're planning on using). As far as the man to man, they are fairly simple. Their main target is really ship to ship (to go with the beautiful resin ships which Flagship makes). We have 10 or so of their ships now and are slowly buying more.

I certainly wouldn't use the rules for strictly man to man, as they aren't that complicated. The ship rules, however, are grand. They're de-finitely targeted at the Warhammer crowd in terms of being fast playing and fun, but those are still good qualities to have. It's not Empire, but it sure is fun. Again, I'm not sure this would apply for strictly man to man...get 3-4 ships out there, though...